Treating blue-green algae with erythromycin. I once treated BGA a while ago with erythromycin using a lower dose of 2.5 mg/liter for 5 days without water change. This is about 100 mg per 10 gallons. After 4 days the color of the BGA turned dark or brown. Now, I have BGA again, but instead of dosing lower, I thought I would try another method.. I'm going to be treating the tank with API E.M. Erythromycin. The treatment has to be dosed at least four times, over the course of several days. However, I keep reading that because erythromycin is an antibiotic, it could kill off my filter's beneficial bacteria and restart the cycle. I can't really afford to have more problems with the.

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Is API E.M. ERYTHROMYCIN™ fish remedy safe to use as a preventative if one fish is sick in a tank with other seemingly healthy fish?. and excess phosphate can cause problematic conditions in your tank. Use the API PHOSPHATE TEST KIT to test for high phosphate levels weekly. It may be used for both marine (saltwater) and freshwater.. Afterwards you must practice good tank hygiene to prevent reintroduction. 1. Nuke them with erythromycin. Erythromycin is an antibiotic intended for this use. Maintaining 2.5 ppm for a week will do the job. Antibiotics will work too, but they can be harder to come by and are more a final measure than a first response.