Citric acid is a major industrial chemical, produced at >2 million t/year worldwide. Its main source is not from fruit, but from the fermentation of crude sugars (e.g., molasses and corn starch) by the mold Aspergillus niger. It has a myriad of uses, mostly in foods and pharmaceuticals; these uses include acidifying agent/pH adjustment.. The citric acid cycle is a closed loop; the last part of the pathway reforms the molecule used in the first step. The cycle includes eight major steps. Simplified diagram of the citric acid cycle. First, acetyl CoA combines with oxaloacetate, a four-carbon molecule, losing the CoA group and forming the six-carbon molecule citrate.

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Citric acid is a weak acid that is found naturally in all citrus fruits. If you've ever sunk your teeth into a lemon, you've tasted citric acid. Manufacturers add a man-made version of it to.. Citric acid, a tricarboxylic acid, has found wide application in the chemical and pharmaceutical industry due to its biocompatibility, versatility, and green, environmentally friendly chemistry. This review emphasizes the pharmaceutical uses of citric acid as a strategic ingredient in drug formulation while focusing on the impact of its.